Updated April 1st 2025, 21:28 IST

Vitamin B12 Deficiency: Are You Ignoring These 9 Warning Signs

One of the first and most common signs of vitamin B12 deficiency is fatigue. Without enough B12, your body struggles to produce red blood cells.

Reported by: Surabhi Shaurya
Vitamin B12 Deficiency: Warning Signs You Shouldn’t Ignore | Image: Freepik

New Delhi: Vitamin B12, also known as cobalamin, is a crucial water-soluble vitamin that plays an essential role in the production of red blood cells, nerve function, and DNA synthesis. Despite its importance, vitamin B12 deficiency is relatively common and can lead to a variety of health issues if left unaddressed.  Since the body doesn’t produce this vitamin naturally, it must be obtained from food sources like meat, dairy products, eggs, and fortified cereals, or through supplements.

However, many people, especially those following a plant-based diet or individuals with certain medical conditions, may find it challenging to get enough vitamin B12. It's essential to recognise the warning signs of vitamin B12 deficiency early, as it can lead to more severe health complications over time. 

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B12 Deficiency: Warning Signs You Shouldn’t Ignore

Below are some of the key symptoms that should not be ignored:

  • Fatigue and Weakness: One of the first and most common signs of vitamin B12 deficiency is fatigue. Without enough B12, your body struggles to produce red blood cells, which carry oxygen throughout your body. A lack of oxygen can leave you feeling exhausted and weak, even after a full night’s rest. If you find yourself constantly tired or lethargic, despite getting adequate sleep, it might be time to check your vitamin B12 levels.
  • Pale or Jaundiced Skin: Vitamin B12 plays an essential role in the production of red blood cells, so a deficiency can lead to anemia. Anemia, in turn, can cause your skin to appear pale. In some cases, a severe deficiency can lead to jaundice, which causes the skin and eyes to turn yellow. If you notice a yellowish tint to your skin or sclera (the white part of your eyes), it is crucial to seek medical attention.
  • Numbness or Tingling Sensations: Vitamin B12 is vital for nerve health. A deficiency can damage the protective covering of nerves, leading to numbness, tingling, or a "pins and needles" sensation, especially in the hands and feet. Over time, this nerve damage can become more severe and even lead to coordination problems and difficulty walking.
  • Difficulty Thinking and Memory Problems: One of the more serious symptoms of vitamin B12 deficiency is cognitive decline. It can impair your ability to think clearly, make decisions, and concentrate. This may even progress to memory loss or confusion, which can sometimes be mistaken for early signs of dementia, particularly in older adults. If you experience mental fog or find it difficult to retain information, it’s important to address the underlying cause promptly.
  • Mood Swings and Depression: Vitamin B12 is involved in the production of brain chemicals such as serotonin and dopamine, which regulate mood. A deficiency can disrupt the production of these chemicals, potentially leading to symptoms of depression, irritability, and anxiety. If you’ve been feeling unusually down or anxious without an apparent reason, vitamin B12 levels might be a contributing factor.
  • Shortness of Breath and Dizziness: Since vitamin B12 plays a role in red blood cell production and oxygen transport, a deficiency can cause shortness of breath and dizziness, especially with physical exertion. This happens because the body is not able to transport oxygen efficiently due to a lack of red blood cells, resulting in fatigue and breathlessness.
  • Glossitis and Mouth Ulcers: A swollen, inflamed, and smooth tongue (known as glossitis) is another common sign of vitamin B12 deficiency. You might notice that your tongue appears smooth, red, or sore. Additionally, mouth ulcers or sores may develop. These symptoms are typically linked to a deficiency in B12, as the vitamin is essential for the health of the tissues in the mouth.
  • Vision Problems: A lack of vitamin B12 can also affect your eyes. The deficiency can lead to damage to the optic nerve, resulting in vision problems such as blurred or double vision. If left untreated, this condition may worsen and potentially lead to permanent vision impairment.
  • Heart Palpitations: Another symptom of vitamin B12 deficiency is an irregular heartbeat, also known as heart palpitations. The deficiency causes a reduction in red blood cell production, which results in anemia and a reduced oxygen supply to tissues and organs. This can cause the heart to work harder to circulate oxygenated blood, leading to palpitations, increased heart rate, and chest discomfort.
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Who’s at Risk for Vitamin B12 Deficiency?

  • Vegetarians and Vegans: Since B12 is predominantly found in animal products like meat, fish, eggs, and dairy, people who avoid these foods are at higher risk for deficiency.
  • Older Adults: As we age, the body’s ability to absorb B12 decreases, leading to a higher risk of deficiency.
  • People with Digestive Disorders: Conditions such as celiac disease, Crohn’s disease, and irritable bowel syndrome (IBS) can interfere with the body’s ability to absorb B12.
  • Pregnant and Breastfeeding Women: Women who are pregnant or breastfeeding may need higher amounts of vitamin B12, and if they don't get enough from their diet or supplements, both the mother and the baby could be at risk.
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How to Address Vitamin B12 Deficiency

If you experience any of the symptoms mentioned above, it’s crucial to consult with a healthcare professional who can perform a blood test to check your vitamin B12 levels. If a deficiency is confirmed, treatment typically involves dietary changes or supplements.

  • Dietary Changes: Incorporating more B12-rich foods into your diet, such as meat, fish, eggs, and dairy products, can help replenish your vitamin B12 levels. For those following a vegetarian or vegan diet, fortified cereals, plant-based milks, and B12 supplements may be necessary.
  • Supplements: If dietary changes are not sufficient or if your body has trouble absorbing B12, your doctor may recommend B12 supplements, which are available in various forms, including oral tablets, sublingual (under-the-tongue) tablets, or even injections in severe cases.

Vitamin B12 deficiency can lead to a range of health problems if not addressed early. The symptoms can be subtle at first but may progressively worsen, leading to irreversible nerve damage and cognitive decline. Recognizing the warning signs, especially if you fall into a high-risk group, can help prevent long-term complications. By taking proactive steps to monitor your vitamin B12 intake and seek treatment when necessary, you can safeguard your health and well-being.

If you suspect a deficiency, don't wait for symptoms to worsen—schedule a checkup with your healthcare provider to ensure you're getting the necessary nutrients your body needs to function optimally.

Published April 1st 2025, 20:11 IST