COVID-19: CBD may help reduce lung inflammation in patients, says study

While scientists across globe search for a vaccine for coronavirus, recent research revealed that Cannabidiol or CBD may help reduce cytokine storm and excessive lung inflammation that is killing COVID-19 infected patients. While scientists ackwledged that more work is required, including clinical trials to determine optimal dos and timing, y also ted that researchers at Dental College of Georgia and Medical College of Georgia have early evidence CBD could help patients showing signs of respiratory distress avoid extreme interventions like mechanical ventilation as well as death from acute respiratory distress syndrome (ARDS).

Dr Babak Baban, immulogist and interim associate dean for research at DCG and corresponding author of study in journal Cannabis and Cannabiid Research, in a statement, said, “ARDS is a major killer in severe cases of some respiratory viral infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and we have an urgent need for better intervention and treatment strategies”. 

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Co-author Dr Jack Yu, who is a physician-scientists and chief of paediatric plastic surgery at MCG, also ded recent research indicate that pure CBD can help lungs recover from overwhelming inflammation, or cytokine storm, caused by dely virus. He furr informed that CDB can restore healthier oxygen levels in body. 

Cannabis calms inflammatory response 

As per study, Baban and Yu took vant of large, unique genetic structure of vel coronavirus. ir model produced classic symptoms of ARDS like overwhelming and destructive immune response and n y found that CBD significantly down-regulated classic indicators of excess, like inflammation-promoting cytokines as it improved oxygen levels in blood and enables lungs to recover from eh structural dam.  

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While pealing how cannabis calmed inflammatory response, Baban said that when infection starts doctors need to immune system to clear virus. He furr explained that in second part, doctors will need to down-regulate it, t stop it but bring down power of inflammatory responses. Yu said that body is fighting infection inside lungs but that response cases dam of its own, n triggers more of a response that becomes ‘self-magnifying’. 

Baban said, “Working in mice, AU researchers were able to recreate severe lung condition and n give m CBD to help block that response and improve lung function and block some dangerous clotting. y also have 'very strong data' that it directly blocks a factor that helps promote inflammation”. 

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