Now, CMFRI comes up with natural remedy for fatty liver disease

In continuation of its major research work on developing natural remedies from marine organisms against various lifestyle diseases, Central Marine Fisheries Research Institute (CMFRI) has come up with a nutraceutical product from select seaweeds to treat non-alcoholic fatty liver disease (NAFLD).

Named CalminTM LivCure extract, product is a unique blend of 100 percent natural bioactive ingredients extracted from seaweeds with an eco-friendly green technology to improve liver health.

This is 9th such product from marine organisms being developed by  CMFRI which alrey h brought out nutraceuticals to combat a series of lifestyle diseases, such as -2 diabetes, arthritis, cholesterol, hypertension, hypothyroidism, and osteoporosis, and to improve immunity, an official statement said here.

Out of se nutraceuticals, eight products are from seaweeds and one from green mussels, it said.

Kajal Chakraborty, Principal Scientist at Marine Biotechnology, Fish Nutrition and Health Division of  CMFRI led research works to develop product. He said that bioactive pharmacophore les from seaweeds were used to develop nutraceutical product.

Pre-clinical trials showed that LivCure extract proved to have potential to inhibit different enzymes and various target receptors associated with dyslipidemia and pathophysiology leing to NAFLD, he said.

''This helps improve liver health, reduce disposition of fatty substances, and maintain or liver/lipid parameters within clinically acceptable limits", expert explained nutraceutical does not have any side effects as established by detailed preclinical trials.

"It has proved that long-term oral ministration of this product will not le to general organ or systemic toxicity", Chakraborty ded.

technology will be out-licensed soon to those in pharmaceutical industry for commercial production of nutraceutical.

For last few years,  CMFRI intensively focuses on research on seaweeds mainly for developing natural products beneficial to improving human health, said A Gopalakrishnan, Director of CMFRI.

"Seaweeds are often termed as wonder herbs of ocean due to ir potential pharmaceutical properties. Recently, this marine macroflora is gaining immense attention in nutraceutical industries due to its protective function against various chronic diseases", he said, ding that intensive and continuous research on extracting bioactive compounds from seaweeds has helped CMFRI win much national recognition, statement ded.