Published 12:19 IST, May 30th 2020
Pangolins may have incubated infectious coronavirus disease: Study
According to a study conducted by researchers, it has been found that novel coronavirus first infected both the bats and pangolins and them jumped to humans.
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According to a study conducted by researchers, it has been found that vel coronavirus first infected both bats and pangolins and n pathogens jumped to human beings. researchers reportedly said that it is too early to blame pangolins for coronavirus pandemic and y believe that a third species of animal must be involved who may have played host to virus before it entered to people. study is published in journal Science vances. A team of researchers from Duke University, Los Alamos National Laboratory reportedly said that it is quite clear that coronavirus has swapped genes repeatedly with similar strains infecting bats, pangolins, and a possible third species.
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About study
As per study, team analyzed 43 complete gemes from three cles of coronaviruses that infect bats and pangolins and resembles to vel coronavirus. According to study it has been found that CoV sequences closely related to SARS-CoV-2 were obtained from confiscated Malaya pangolins in two separate studies. It ded that se pangolin SARS-like CoVs form two distinct cles corresponding to ir locations of origin: first cle, Pan_SL-CoV_GD, sampled from Guangdong (GD) province in China, is genetically more similar to SARS-CoV-2 (91.2%) than second cle, Pan_SL-CoV_GX, sampled from Guangxi (GX) province (85.4%).
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study says, "Understanding origin of SARS-CoV-2 may help develop strategies to deter future cross-species transmissions and to establish appropriate animal models. Recombination plays an important role in evolution of coronaviruses." It ded, "Viral sequences nearly identical to SARS and MERS viruses were found in civets and domestic camels, respectively, demonstrating that y originated from zootic transmissions with intermediate host species between bat reservoirs and humans—a common pattern leing to CoV zoosis.
However, n-human viruses nearly identical to SARS-CoV-2 have t yet been found. In this paper we demonstrate, through localized gemic analysis, a complex pattern of evolutionary recombination and strong purifying selection between CoVs from distinct host species and that cross-species infection that likely originated SARS-CoV-2.
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Im Credit: Pixabay
12:19 IST, May 30th 2020