Scientists discover first ever species to alter genetic component outside nucleus

Scientists have reportedly discovered that squid can edit ir own genetic composition t only within nucleus of ir neurons but also within axon, long, slender neural projections that transmit electrical impulses in its body, according to research. This is first-ever discovery of a species capable of editing its genetic information outside of nucleus of cell. 

According to study, led by Isabel C. Vallecillo-Viejo and Joshua Rosenthal at Marine Biological Laboratory (MBL), Woods Hole, published in  Nucleic Acids Research,  research is key to defying  "central dogma" of molecular biology, which states that genetic composition of species is derived from DNA. However, Rosenthal and co-research scientists discovered that squid could transform genetic information, altering  messenger RNA instructions to an extraordinary degree. study indicates that y could also edit type of protein which has to be produced in nervous system. This is why, squid can alter colour, and squirt ink, because y can tweak ir RNA component. 

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Octopus relied on RNA editing

“But we thought all RNA editing happened in nucleus, and n modified messenger RNAs are exported out to cell,” Rosenthal, senior author on present study, wrote in research blog. “w we are showing that squid can modify RNAs out in periphery of cell. That means, oretically, y can modify protein function to meet localized demands of cell. That gives m a lot of latitudes to tailor genetic information, as needed,” she added. team also showed that messenger RNAs are edited in nerve cell’s axon at much higher rates than in nucleus, study revealed. 

According to research document, scientists from Tel Aviv University and University of Colorado at Denver collaborated with MBL scientists to conduct findings. “Previously, Rosenthal and colleagues showed that octopus and cuttlefish also rely heavily on mRNA editing to diversify  proteins y can produce in nervous system. Toger with squid, se animals are kwn for strikingly sophisticated behaviors, relative to or invertebrates”, research study furr revealed.  

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