China approves drug to cure Alzheimer's; to go on sale from next month

A home-grown drug in China for Alzheimer's, which could treat ailment in 17 years, will be available to Chinese patients from next month after it was officially approved, its developers said. China's National Medical Products ministration has approved market launch of drug, GV-971, last Saturday which could treat ailment in 17 years, state-run China Daily reported on Monday.

home-grown drug in China for Alzheimer's will be available to patients

Patients will be able to buy drug around China from December 29, and more production lines will grually be put into operation to satisfy market demand, according to Shanghai Green Valley Pharmaceutical, one of drug's developers. drug is only Alzheimer's medicine out of more than 320 developed by pharmaceutical companies around globe to survive clinical trials, despite investment of hundreds of billions of US dollars over past two deces, report said.

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Alzheimer drug extracted from brown algae

Extracted from brown algae, orally taken drug is world's first multi-targeting and carbohydrate-based drug for Alzheimer's, ministration said. It can treat mild to moderate forms of disease and improve cognition, it said. first production line for drug, which will meet needs of two million patients, will begin running this week.

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About Alzheimer's disease

Alzheimer's disease, an irreversible and progressive brain disorder that slowly destroys memory, thinking ability and capability to carry out simple tasks, affects at least 50 million people worldwide, and number is expected to increase as populations . China has roughly 10 million people with Alzheimer's, highest in world.

Chinese Acemy of Sciences' Shanghai Institute of Materia Medica, which jointly developed GV-971 with Green Valley and Ocean University of China after 22 years of research, said re were previously five medicines with limited efficacy used to treat disease, which was discovered a century ago.

A phase III clinical trial of drug involving 818 patients completed in July last year h "proven to continuously and effectively improve cognition among mild to moderate Alzheimer's disease sufferers over a period of nine months," said Geng Meiyu, le researcher on drug and a researcher with SIMM. "diction and serious toxicity of rapy haven't been identified in research so far," she said.

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functioning of drug

Scientists said drug functions mainly by rebalancing gut microbiota, reducing neuro-inflammation and reducing cognitive impairment. Some doctors from home and abro, including David Holtzman, chairman of American Neurological Association, said y believe GV-971 will provide a new medical solution for patients.

Preparations are being me for drug's clinical trials in US and international multi-centre research, its developers said, with initial communication with US Food and Drug ministration alrey completed.

"Green Valley has established a professional team and hired world-rewned experts in this field as consultants in preparation for initiating clinical trials in US," said Lyu Songtao, company's chairman.

"We don't exclude possibility of collaborating with international research institutions to perform clinical trials in US," Daily report quoted Lyu as saying.

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