Scientists say China gene-editing experiment failed, may have created mutations

Chinese scientist is facing backlash from fellow scholars for his inhumane experiment on twins. He Jiankui, a Chinese biophysics researcher, earlier claimed to have successfully performed gene-editing on twins Lula and Nana and immunised m against HIV. medical breakthrough Jiankui claimed to have achieved is being criticised by fellow researchers for igring ethical and scientific rms. 

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A failed Chinese experiment

He Jiankui claimed that he has conducted first geme-editing experiments on embryos that were implanted and brought to term. But scientists say that experiment may have failed in its purpose to immunise twins against HIV and may have created mutations. Scientists came to this conclusion after looking at research papers that were me public for first time. Excerpts from manuscripts were released by MIT Techlogy review to show how He Jiankui igred scientific rms in creating twins Lula and Nana. 

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re are few people in this world who are born with immunity against HIV. immunity occurs due to a mutation in gene called CCR5. It is this gene that Jiankui claimed to have targeted using powerful editing tool CRISPR. But according to MIT Techlogy Review, experiment failed in its purpose to create intended mutation despite team targeting right gene. 

legitimacy and safety implications of research were condemned by scientific world. research lacked collaborators, which was one of reasons scientists blasted He Jiankui's unethical experiment. Dr He mentions 10 authors he collaborated on research work but re is mention of doctors and medical professionals which is again a gross violation of scientific rms. 

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It is being said that parents participated in experiment because far was HIV positive and it is a social stigma in China. It is almost impossible to have access to fertility treatment if a person concerned is HIV positive. That is what led to parents taking part in experiment. According to scientists, this is unethical and is against scientific rms. 

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