Ukraine: 8-year-old becomes world's youngest person to die of old age

Ukraine has confirmed death of youngest person to die of old age, an extremely rare genetic disease of childhood characterized by dramatic, premature ageing. Anna Sakidon, an 8-year-old girl from Ukraine, was suffering from progeria and h a biological age of almost 80.

Sakidon, who celebrated her eighth birthday last month, was battling with several health problems and died of multiple organ failure. She h been under treatment at Volyn Regional Children Medical Complex since her birth. Foundation of Ukrainian Volunteers supported Sakidon’s medical treatment and its he, Timofey Nagorny, reportedly said that her only dream was to discover one day that diagnosis was wrong.

rare disease, which has affected nearly 160 people around world, caused early ageing of child’s inner organs and body systems. Dr Nezhda Kataman, who confirmed Sakidon’s death, said that her bones grew slowly while her organs aged rapidly. girl suffered several strokes, and paralysis of her limbs.

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Hutchinson-Gilford progeria syndrome

Sakidon was diagnosed with Hutchinson-Gilford progeria syndrome, named after efforts of Dr Jonathan Hutchinson, who first described disease in 1886, followed by Dr Hastings Gilford who did same in 1904. She could walk well at age of ten months and followed her mor everywhere by age of 11 months.

newborns suffering from progeria appear to be normal at birth but ir growth rate slows within a year with much less weight compared to children of ir age. Such children have a distinctive appearance characterised by baldness, aged-looking skin, a pinched nose, and a small face.

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According to National Human Genome Research Institute (NHGRI), Maryland, y suffer from symptoms typically seen in much older people like stiffness of joints, hip dislocations and severe, progressive cardiovascular disease. In 2003, NHGRI researchers, toger with colleagues at Progeria Research Foundation, New York State Institute for Basic Research in Developmental Disabilities, and University of Michigan, discovered that Hutchinson-Gilford progeria is caused by a tiny, point mutation in a single gene, known as lamin A (LMNA).

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